Devils's claw (Harpagophytum procumbens): pharmacological and clinical studies.
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چکیده
منابع مشابه
Devils's claw (Harpagophytum procumbens): pharmacological and clinical studies.
Devil's claw (Harpagophytum procumbens): pharmacological and clinical studies SIR, Over the last few years a number of reports have appeared in local newpapers in the North of England and Scotland claiming 'miraculous' results for treatment with devil's claw in patients with both adult and juvenile rheumatoid arthritis.1 2The preparation used was a tablet prepared from an aqueous extract of the...
متن کاملDevil's Claw to Suppress Appetite—Ghrelin Receptor Modulation Potential of a Harpagophytum procumbens Root Extract
Ghrelin is a stomach-derived peptide that has been identified as the only circulating hunger hormone that exerts a potent orexigenic effect via activation of its receptor, the growth hormone secretagogue receptor (GHS-R1a). Hence, the ghrelinergic system represents a promising target to treat obesity and obesity-related diseases. In this study we analysed the GHS-R1a receptor activating potenti...
متن کاملHarpagophytum procumbens (Devil's Claw): A Possible Natural Anti-Inflammatory Agent (An Experimental Study)
Extract of Harpagophytum procumbens (devil's claw) has become the focus of research as a potential therapeutic agent in the treatment of rheumatic arthritis and pain due to its favorable side effects profile compared to synthetic alternatives. This superior safety of treatment is very valuable, especially in view of that in mandatory long duration of therapy in chronic diseases. None of NS...
متن کاملThe quality of clinical trials with Harpagophytum procumbens.
OBJECTIVE To examine systematically the quality of the clinical trials investigating the effectiveness of Harpagophytum products. METHODS Literature searches and enquiries to experts identified 20 studies of treatment with various Harpagophytum products (powder, aqueous and ethanolic extracts) for exacerbations of chronic musculoskeletal pain. Eight were open uncontrolled observational studie...
متن کاملDevil's Claw (Harpagophytum procumbens) as a treatment for osteoarthritis: a review of efficacy and safety.
BACKGROUND Osteoarthritis (OA) is a highly prevalent musculoskeletal disorder. Conventional treatment (i.e., the use of nonsteroidal anti-inflammatory drugs-NSAIDs) is associated with well-documented adverse effects. Devil's Claw (Harpagophytum procumbens) a traditional South African herbal remedy used for rheumatic conditions, may be a safer treatment option. To date, 14 clinical trials have a...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1981
ISSN: 0003-4967
DOI: 10.1136/ard.40.6.632